Molecular retaliation of muscle to varying exercise established according to a study by Arizona State University (ASU) and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope. Exercise can be fashioned for individuals based on genomics.

For years scientists have researched the impacts of varying exercise on human body but never prior to this molecular accuracy according to the TGen-ASU study published in the Journal of Applied Physiology. Dr. Matt Huentelman, professor in TGen’s Neurogenomics Division, and one of the study’s senior authors said that we aspire to influence these findings into more accurate exercise guidance in the future; ones that are adapted to an individual not only depended on their physiological requirements but also based on their molecular response to exercise.

This study commences to designate some of the molecular alterations that take place in muscle tissue succeeding varying types of exercise notably resistance exercise (lifting weights), versus that of aerobic exercise (in this study, cycling).

Researchers utilized progressive technology, whole-transcriptome RNA sequencing, to recognize genes that were impacted exceptionally by each type of exercise. Muscle specimens were acquired by six men ages 27-30, before their exercises, and again at 1 hour and 4 hours following both weight lifting and cycling.

The study yielded the result that 48 distinctive genes succeeding aerobic exercise and 348 distinct genes succeeding weight lifting that were disparately expressed. This means that exercises boosted the genes and rendered them more powerful or then less powerful like a dimmer switch on a chandelier.