Insulin like hormones potentially causes disease as each cell in your body answers to the hormone insulin and if that procedure starts to yield negative results then you are bound to get diabetes. In an accidental discovery scientists at Joslin Diabetes Center have discerned four viruses that can yield insulin-like hormones which are very much agile on human cells. The findings accompany new potential for disclosing biological mechanism that may result in diabetes and cancer.
Emrah Altindis, PhD, a Joslin research fellow and lead author on a paper in the journal PNAS on the work said that their research may assist in rendering a novel field that we may vociferate as microbial endocrinology. We display that these viral insulin-like peptides work on human and rodent cells. With a huge number of microbial peptides to which we are revealed, there is a new opportunity for host-microbe synergy. We understand that researching these procedures will assist in comprehending the role of microbes in human disease.
Ronald Kahn, MD, Joslin’s chief academic officer and senior author on the paper said that the findings of viral insulin-like hormones does emanate the question what role might they be playing in diabetes as well as autoimmune disease, cancer and other metabolic conditions.
The central idea for probe came when Altindis, whose previous research concentrated on generating vaccines against bacteria, frequented a Joslin seminar that disputed possible causes of autoimmune reaction that drives type 1 diabetes. He commenced to formulate if bacteria or viruses could generate insulin-like peptides that could assist in catapulting the disease.